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We investigate molecular mechanisms and therapeutic strategies for frontotemporal dementia and amyotrophic lateral sclerosis at the UCL Institute of Neurology and the UK Dementia Research Institute at UCL.

Find out more on our research page.

News

Congrats to Jack on his new paper on FUS autoregulation and splicing

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Jack´s new paper: FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention. Humphrey J, Birsa N, Milioto C, McLaughlin M, Ule AM, Robaldo D, Eberle AB, Kräuchi R, Bentham M, Brown AL, Jarvis S, Bodo C, Garone MG, Devoy A, Soraru G, Rosa A, Bozzoni I,…

Congratulations to Bhavana for becoming an independent PI!

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Good luck with setting up your new lab at the Institute for Stem Cell Biology and Regenerative Medicine (inStem), Bangalore, India. 

Adrian presented at the Packard Centre for ALS Annual Symposium

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Adrian presented our recent work on developing new C9orf72 knock-in models at the Packard Centre for ALS Annual Symposium in Baltimore March 2nd-3rd 2020.

2nd European C9orf72 Meeting: Hosting in London Jan 30-31st

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We are looking forward to the 2nd European C9orf72 Meeting January 30-31st 2020. This year the meeting is hosted by the Isaacs lab at UCL!