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Isaacs Lab

New Publication in Acta Neuropathologica Comms: Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS

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We are pleased to announce our article, in collaboration with Dr. Tammaryn Lashley of the UCL Brain Bank, published in Acta Neuropathalogica Communications: Gittings, LM, Foti, SC, Benson, BC, Gami-Patel, P, Isaacs, AM, Lashley, T. Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS.. Acta Neuropathol Commun….

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New Publication in Acta Neuropathalogica: C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A

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We are excited to announce our new article published in Acta Neuropathalogica: Moens, TG, Niccoli, T, Wilson, KM, Atilano, ML, Birsa, N, Gittings, LM, Holbling, BV, Dyson, MC, Thoeng, A, Neeves, J, Glaria, I, Yu, L, Bussmann, J, Storkebaum, E, Pardo, M, Choudhary, JS, Fratta, P, Partridge, L, Isaacs, AM….

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1st European C9orf72 Workshop

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The first of it’s kind, a meeting of European scientists working on C9orf72 FTD/ALS co-organised by Adrian and Dieter Edbauer (DZNE, Munich), aiming to encourage new collaborations. This was a fantastic meeting with all speakers presenting unpublished data and it helped encourage the sharing of resources and new collaborations, significantly…

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UK DRI: Connectome 2018 Event

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Several members of the lab attended the first UK DRI Connectome event. Adrian and Teresa both gave talks as did Sarah Mizielinska, an Isaacs Lab alumnus who has recently opened her own lab at the UK DRI at King’s College London. This event allowed UK DRI groups to showcase their…

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