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We investigate molecular mechanisms and therapeutic strategies for frontotemporal dementia and amyotrophic lateral sclerosis at the UCL Institute of Neurology and the UK Dementia Research Institute at UCL.

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New publication: Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

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We are excited to be part of Fratta lab’s new paper: Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo…

Congratulations to Dr Moens!

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Congratulations to our PhD student Thomas Moens for passing his viva. Tom will be moving to Belgium to continue his research on ALS. We are very proud!

New paper: Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD

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Our new paper Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD (Moens et al.) is now published on Acta Neuropathologica March 2018, Volume 135, Issue 3, pp 445–457

Congratulations to Annalisa for passing her Viva

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We are so proud to announce our latest PhD from the lab – Annalisa Cavillini.