New Publication in Acta Neuropathologica Comms: Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS

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We are pleased to announce our article, in collaboration with Dr. Tammaryn Lashley of the UCL Brain Bank, published in Acta Neuropathalogica Communications: Gittings, LM, Foti, SC, Benson, BC, Gami-Patel, P, Isaacs, AM, Lashley, T. Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS.. Acta Neuropathol Commun….

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New Publication in Acta Neuropathalogica: C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A

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We are excited to announce our new article published in Acta Neuropathalogica: Moens, TG, Niccoli, T, Wilson, KM, Atilano, ML, Birsa, N, Gittings, LM, Holbling, BV, Dyson, MC, Thoeng, A, Neeves, J, Glaria, I, Yu, L, Bussmann, J, Storkebaum, E, Pardo, M, Choudhary, JS, Fratta, P, Partridge, L, Isaacs, AM….

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New Publication in Brain: Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.

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We are excited to announce our new article published in Brain: Clayton, EL, Milioto, C, Muralidharan, B, Norona, FE, Edgar, JR, Soriano, A, Jafar-Nejad, P, Rigo, F, Collinge, J, Isaacs, AM. Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown. Brain. 2018;141 (12):3428-3442. Please see our publication page…

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1st European C9orf72 Workshop

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The first of it’s kind, a meeting of European scientists working on C9orf72 FTD/ALS co-organised by Adrian and Dieter Edbauer (DZNE, Munich), aiming to encourage new collaborations. This was a fantastic meeting with all speakers presenting unpublished data and it helped encourage the sharing of resources and new collaborations, significantly…

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