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We investigate molecular mechanisms and therapeutic strategies for frontotemporal dementia and amyotrophic lateral sclerosis at the UCL Institute of Neurology and the UK Dementia Research Institute at UCL.

Find out more on our research page.

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A web and twitter resource providing jargon free updates for the whole FTD community


New publication: Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

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We are excited to be part of Fratta lab’s new paper: Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo…

Congratulations to Dr Moens!

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Congratulations to our PhD student Thomas Moens for passing his viva. Tom will be moving to Belgium to continue his research on ALS. We are very proud!

New paper: Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD

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Our new paper Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD (Moens et al.) is now published on Acta Neuropathologica March 2018, Volume 135, Issue 3, pp 445–457

Congratulations to Annalisa for passing her Viva

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We are so proud to announce our latest PhD from the lab – Annalisa Cavillini.