Our PhD student Jack Humphrey reported that TDP-43 but not FUS affects cryptic splicing. Read it here at BMC Genomics.
Our third year PhD student Thomas Moens recently published a review on genetic models of C9orf72FTD/ALS. Read it here.
Our latest publication is now out on Acta Neuropathologica Communications. Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
We are hiring for a full-time technician position. You will be based in IHA in the Drosophila lab working with experienced and enthusiastic postdocs on the role of C9orf72 in ALS Drosophila model. More info here.
We welcome two new postdocs Bhavana Muralidharan and Magda Atilano into our lab.
Our PhD student Rubika presented at the Fifth Annual Postgraduate Research Symposium hosted by the UCL Faculty of Brain Sciences and was awarded the first prize for the 3 Minute Thesis (3MT) competition. She will now go forwards to represent the Faculty of Brain Sciences at the UCL 3MT competition.
Our latest paper on FTD caused by CHMP2B and the role of microglia has just come out in Human Molecular Genetics. Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation. Clayton EL et al. Frontotemporal dementia (FTD)-causing mutations in the CHMP2B gene lead…
Adrian gave a talk on Jan 17th at the MRC Harwell Institute, Mammalian Genetics Unit, about our work on C9orf72 FTD and ALS