We investigate molecular mechanisms and therapeutic strategies for frontotemporal dementia and amyotrophic lateral sclerosis at the UCL Institute of Neurology and the UK Dementia Research Institute at UCL.
Find out more on our research page.
News
The entire lab attended the annual DRI event in Harrogate, where we enjoyed engaging talks (including one by Alex), a variety of posters, and plenty of insightful discussions. It was a great opportunity to reconnect with familiar faces and meet new ones. Looking forward to next year!
In2Research summer placement student Aaliyah presented her research at the Royal Institution as part as the In2Research Celebration Event.
We developed new polyGR and polyPR knock-in mice that developed features of ALS and surprisingly had a neuroprotective extracellular matrix response. An epic effort by lead author Carmelo and many lab members and collaborators including Elizabeth Fisher at UCL. Covered by Alzforum: https://www.alzforum.org/news/research-news/neuroprotective-extracellular-matrix-seen-c9orf72-alsftd-models and more info here: https://ukdri.ac.uk/news-and-events/protective-response-to-early-changes-in-als-and-ftd