For the Neuro Podcases Clinical Neuroscience Podcast he talked about some of the labs’ early work and our latest projects developing gene therapies and a new role for lipids in ALS/FTD:
Read More
Congrats to Ashling, Alex and the rest of the team! Check it out here: https://www.nature.com/articles/s41593-025-01889-3
The entire lab attended the annual DRI event in Harrogate, where we enjoyed engaging talks (including one by Alex), a variety of posters, and plenty of insightful discussions. It was a great opportunity to reconnect with familiar faces and meet new ones. Looking forward to next year!
In2Research summer placement student Aaliyah presented her research at the Royal Institution as part as the In2Research Celebration Event.
We developed new polyGR and polyPR knock-in mice that developed features of ALS and surprisingly had a neuroprotective extracellular matrix response. An epic effort by lead author Carmelo and many lab members and collaborators including Elizabeth Fisher at UCL. Covered by Alzforum: https://www.alzforum.org/news/research-news/neuroprotective-extracellular-matrix-seen-c9orf72-alsftd-models and more info here: https://ukdri.ac.uk/news-and-events/protective-response-to-early-changes-in-als-and-ftd
Adrian gave an update on our latest ALS research to the Packard Center Symposium in Baltimore
We are excited to be presenting at the largest international conference on ALS. Alex will present our exciting new data on lipid dysregulation in ALS and Adrian on FTD/ALS modelling and therapeutics.