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Adrian Isaacs

New Publication in acta neuropathalogica: Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity.

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We are pleased to announce the publication of our paper in Acta Neuropathalogica: Gittings, LM, Boeynaems, S, Lightwood, D, Clargo, A, Topia, S, Nakayama, L, Troakes, C, Mann, DMA, Gitler, AD, Lashley, T, Isaacs, AM. Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR…

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New Publication in Brain: Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.

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We are excited to announce our new article published in Brain: Clayton, EL, Milioto, C, Muralidharan, B, Norona, FE, Edgar, JR, Soriano, A, Jafar-Nejad, P, Rigo, F, Collinge, J, Isaacs, AM. Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown. Brain. 2018;141 (12):3428-3442. Please see our publication page…

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