Our latest paper showing G-quadruplex-binding small molecules reduce pathology in C9orf72 iPSC-neurons and Drosophila models is just out in EMBO Molecular Medicine – early online version can be found here
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Our lab head Adrian is giving a talk on C9orf72 at the University of Oslo on Friday Nov 10 as part of a workshop “Model Systems to Investigate Neurodegeneration”
Our PI Dr Isaacs is giving a lecture at University of Edinburgh on 26th of September 2017 as part of UE Neuroscience Seminar. The talk is titled “C9orf72 FTD and ALS – Mechanisms and therapeutics” and will be given at Lecture Theatre A, Chancellors Building, 13:00.
Our lab head Dr Adrian Isaacs will be giving a talk on our C9orf72 work at the Alzheimer’s Association International Conference in London in July
Our news and views article on the development of new biomarkers for C9orf72 FTD/ALS is now out in EMBO Molecular Medicine.
Our PhD student Jack Humphrey reported that TDP-43 but not FUS affects cryptic splicing. Read it here at BMC Genomics.
Our third year PhD student Thomas Moens recently published a review on genetic models of C9orf72FTD/ALS. Read it here.
Our latest publication is now out on Acta Neuropathologica Communications. Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration
We are hiring for a full-time technician position. You will be based in IHA in the Drosophila lab working with experienced and enthusiastic postdocs on the role of C9orf72 in ALS Drosophila model. More info here.